The General Practice Research Database (GPRD) is the world’s largest computerised database of well-validated longitudinal patient records collected through the universal primary care system operated within the UK National Health Service (NHS).
The General Practice
Research Database: Now and the Future
INTRODUCTION
The
General Practice Research Database (GPRD) is the world’s largest computerised
database of well-validated longitudinal patient records collected through the
universal primary care system operated within the UK National Health Service
(NHS). Almost all inhabitants are registered with a single general practice.
Hospitals are required to inform general practitioners (GPs) of any significant
medical events that occur in their patients. Long-term care of chronic
conditions is typically managed by GPs. As a consequence, patients’ medical
records as managed by the GPs contain longitudinal information on all
significant medical events and prescribing. They are essentially the lifelong
record for each patient and include the key secondary care information as well
as laboratory, other investigations and details of all medications prescribed
within general practice. These GP records contain unique information for
research.
The
GPRD contains the anonymised patient medi-cal records from GPs who use the Vision
IT system from InPractice System Ltd (INPS) and who allow the data to be
exported from their clinical system to the GPRD. Only practices that meet
continuous quality standards are included in the GPRD. At present, data are
collected from over three million active patients throughout the United
Kingdom, representing approx-imately 5% of the UK population. Longitudinally,
it now includes twelve million ever-registered patients. The total amount of
follow-up in the GPRD is as of 2006 over 46 million patient-years.
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