Nonmercurial diuretics : Xanthine diuretics : Properties, Synthesis and Drug Profile
Synthesis and drug profile of Caffeine, Theophylline, and Theobromine are discussed under sec III, Chapter CNS Stimulants. The Xanthines (caffeine, theophylline, and theobromine) have a weak diuretic activity. They have been known for their diuretic action, but currently it is rarely used. Aminophylline (theophylline ethylene diamine) is the most used member. Theophylline exerts its diuretic action by inhibition of Na+ reabsorption in the proximal convoluted tubule. These drugs increase renal plasma flow, promoting a higher glomerular filtration rate. Adverse effects are central nervous system (CNS) stimulation and vomiting.SYNTHESIS AND DRUG PROFILE
Nonmercurial diuretics
Xanthine diuretics
Properties
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