The influences of evolving technologies on drug discovery are evident at all stages.
Summary and
outlook to the future
Drug
discovery is inherently a complex, multidisciplinary endeavor that requires
close collaboration of highly skilled professionals, integration of each
disciplines output, and relatively long timelines with different stages of
development that have stage gates to check the progression of the com-pound to
later stages of development and commercialization. This process is also
continuously evolving as the drug targets change, pressures on the
biopharmaceutical industry increase, and our understanding of the fundamental
mechanisms improve. Teamwork and collaboration form the hallmarks of cultural
norms required in this high-paced environment. In addition, idiosyncratic
cross-functional application plays a unique role in breakthrough drug
discovery.
The
influences of evolving technologies on drug discovery are evident at all
stages. For example, big data and trend analysis is helping in deci-sion making
at all stages of development. Greater ability for clinical monitoring and
preclinical toxicology assessment is enabling the development of safer drugs
and early assessment of potential toxicological liabilities. Increasingly,
drugs are being developed in patient-centric manner to serve the needs of given
subpopulations of patients.
Recent
trends in drug development also highlight the increasing use of the outsourcing
model to allow investment of scarce internal resources on the highest-value
items. Typical modern-day biopharmaceutical com-panies collaborate with several
contract research organizations (CROs), contract manufacturing organizations
(CMOs), and academia alike to exe-cute just about every step of the drug
discovery and development process. Organizations increasingly focus on
generating intellectual property and maximizing the speed to market while
maintaining and improving product quality outcomes. These internal emphases
with external forces make the industry a continuously evolving endeavor.
Related Topics
TH 2019 - 2024 pharmacy180.com; Developed by Therithal info.