Pastes

| Home | | Pharmaceutical Drugs and Dosage | | Pharmaceutical Industrial Management |

Chapter: Pharmaceutical Drugs and Dosage: Semisolid dosage forms

Pastes are semisolid dosage forms that contain a large proportion of solid component.


Pastes

Pastes are semisolid dosage forms that contain a large proportion of solid component. They differ from ointments in their consistency, as they contain larger amounts of solids and consequently are thicker and stiffer. Pastes can be made either of fatty bases, such as petrolatum and hydrophilic petrolatum, or of aqueous gels, such as celluloses. Pastes may contain one or more drug substances intended for topical application.

Pastes are well adsorbed on the skin. Pastes can absorb watery solu-tions so that they can be used around oozing lesions. Pastes can be easily removed from skin and are water washable, which is an important consid-eration when they are applied on traumatized skin.

Pastes that contain hydrophobic components can be water impermeable and prevent dehydration. Examples of pastes include the commonly used tooth-pastes and zinc oxide paste. Toothpaste contains an abrasive solid for cleansing purposes and sometimes also includes a fluoride salt, such as sodium fluoride or stannous fluoride, as a medicament. Zinc oxide paste is typically composed of 25% w/w zinc oxide, 25% w/w starch, and 50% w/w white petrolatum.

Pastes can be formed from several bases, such as gelatin, starch, traga-canth, polyethylene glycol, pectin, or cellulose derivatives.

Contact Us, Privacy Policy, Terms and Compliant, DMCA Policy and Compliant

TH 2019 - 2024 pharmacy180.com; Developed by Therithal info.