Biological Source Colocynth is the dried pithy pulp of the ripe fruits of Citrullus colocynthis Schrader, belonging to family Cucurbitaceae.
COLOCYNTH
Synonyms
Bitter apple, Fructus colocynthidis, Colocynthis.
Biological Source
Colocynth is the dried pithy pulp of the ripe fruits of Citrullus colocynthis Schrader,
belonging to family Cucurbitaceae.
Geographical Source
Cultivated in Asia, Africa, South Europe; mainly in Syria,
Cyprus, and Egypt. In India, it is cultivated in Gujarat, Punjab, Tamil Nadu,
etc.
Collection
The plant is perennial prostrate herb. It is rarely
cultivated. The fruits are fleshy in nature and are collected in autumn, when
they are ripe. The ripe fruits are yellow in colour. The fruits are peeled
using a knife and dried under the sun or artificially.
Description
The fleshy fruits are 5 to 8 cm in diameter, subspherical
berry, almost white, and the density is very less. On the outer surface it has
rind and impressions of the knife. Three splits of placenta, which run from
centre to periphery is seen if the fruit is cut transversely. It has two groups
of seeds near the periphery and the remaining portion filled with pithy
parenchyma. It has characteristic odour and intense bitter taste.
Microscopy
The epicarp has the epidermis made of the polygonal cells,
which are covered by a thick cuticle. The cuticle consists of few large
stomata. Below the epidermis it has thin-walled parenchymatous cells and thick
layer of lignified sclerenchymatous tissues. Sclereides are of three layers and
the outermost layer is more lignified than the inner layer of sclereides. The
pulp consists of large parenchyma cells with intercellular space and few narrow
vascular strands which are scattered. The seeds consist of palisade epidermis
of polygonal prismatic cells. The testa consists of thick sclerenchyma which is
eight to ten-celled thick, whereas a collapsed parenchyma is four to five-celled
thick. The embryo consists of thin cellulosic parenchyma containing aleurone
grains and fixed oil.
Chemical Constituents
Alkaloid is the main constituent present in the pulp of
colocynth. Colocynth also contains amorphous resins that are ether and chloroform
soluble. The other constituents are a crystalline dihydroxy alcohol
(citrullol), glycosides of α-elaterin or cucurbitacin E,
elatericin B or cucurbita-cin, dihydroelatericin B, or cucurbitacin L, fixed
oil, and starch.
Uses
It is a hydrogogue purgative; stimulates or irritates the
gastrointestinal tract. It is also prescribed with carminatives and used as an
insecticidal.
Marketed Products
It is one of the ingredients of the preparation known as The
Body Pure (HerbsForever Inc.).
Related Topics
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